Raw material of Fucoidan is Okinawa okamuranus only
High purity of Okinawa okamuranus（Over 80％ contents in powder）
Small and easy to drink tablet（ Expiration date: 2 years ）
Comparison with other products.
Fucoidan is a general term for a water-soluble polysaccharide
Raw materials of fucoidan are from Mozuku, kelp, seaweed
Each material has a different structural formula
Each manufacturer has different procedure of extractions and production
For those reasons, it is not impossible to compare the “mg” simply
Our strengths
In all of those products, we only have many evidences.
Especially the paper about liver cancer is used by our products.
We have the data for “Gastric ulcer”. (In Japanese)
It’s enough for gastric ulcer to take 100mg/day.
We recommend 100-300mg / day. (Absorption rate is different for different people)
Our products (50mg/ tablets) are easy to control for intake per day.
FAQ
1.The meaning “Anti-blood clotting action is very weak.”
First fucoidan is included in the category of “sulfated polysaccharide”.
Chondroitin sulfate and heparin are in the same sulfated polysaccharides.
With respect to blood clotting, heparin is used as a drug of anti-blood clotting.
Since fucoidan also the same category as heparin, we have implemented the test of blood clotting action.
The result is that the anti-blood clotting effect is weak.
Therefore, in the case of fucoidan is in contact with the bleeding ulcers part, if it has strong anti-blood clotting action, we need to check the side effect of increasing the bleeding.
2.Is it contained more than 40mg fucoidan if 50mg of “purity of 80% or more”?
That’s right.
When you want to 100mg formulation of Fucoidan, it will be referred to 100mg ÷ 0.8 = 125mg.
But each Fucoidan still has a difference of structural formula.
Fucoidan included in OKINAWA okamuranus
Fucoidan is a sulfated polysaccharide that is included most in Okinawa mozuku. Okinawa okamuranus fucoidan has revealed a variety of physiological activities, such as gastric ulcer preventive effect, intestinal regulation action immune and an activating action. In addition, the other derived from seaweed fucoidan has a strong anti-blood clotting action but Okinawa okamuranus fucoidan has a very weak feature.
It does not contain other polysaccharides, such as alginic acid in Okinawa mozuku. Therefore, it is possible to produce high-purity fucoidan.
Fucoidan Effectiveness
Activation of cell immune system
Fucoidan derive apoptosis strongly for lymphocyte and leukemia cell.
The biological properties of Fucoidan as either immuno-stimulators or apoptosis inducers may be dependent on molecular weight, or differences in the components of polysaccharides.（1）
Anti-inflammatory effect
The levels of IL-6 mRNA in colonic epithelial cells was lower in colitis-induced Balb / c mice fed Cladosiphon fucoidan than those fed a standard diet.
Fucoidan improves murine chronic colitis by down-regulating
the synthesis of IL-6 in the colonic epithelial cells.
Fucoidan derived from C. o. Tokida may be useful as a dietary substance for the patients with inflammatory bowel disease.（2）
Gastritis prevention
Cladosiphon Fucoidan is a safe substance with potential for gastric protection and may deserve particular attention as a safe agent that can prevent H. pylori infection and reduce the risk of associated gastric cancer.（3.4）
Daily intake of Fucoidan has useful to the prevention and eradication of H. pylori and non-ulcer dyspepsia.（5）
Improvement for gastric motility （6）
Anti tumor effect
Fucoidan exhibits antitumor activity toward Huh7 cells through the downregulation of CXCL12 expression and has a potential therapeutic effect on HCC. （7.8）
Fucoidan is a potentially useful therapeutic agent for patients with ATL.（9）
The oversulfated fucoidan induced apoptosis via caspase-3 and -7 activation-dependent pathway.（10）
Anti-fibrotic effect
As anti-fibrotic mechanism of Fucoidan, TGFβ1 suppression, suggesting that through inhibition and free radical scavenging action CXCL12.（11）
Anti-obesity effect（12）
Fucoidan controls lipolysis depending on concentration. It significantly declines the contents of neutral fat.
Anti-blood clotting activity（13）
Fucoidan has a heparin-like bioactive, anticoagulant activity and antithrombotic effect.
References
Topics
Effects of Fucoidan on Hepatitis C Virus
Hepatitis C Virus Has Infected 4.5 Million Vietnamese
